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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
19.39
Human Site:
S472
Identified Species:
35.56
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S472
E
P
G
D
G
L
S
S
P
A
G
G
S
Y
E
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S472
E
P
G
D
G
L
S
S
P
A
G
G
S
Y
E
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
S452
R
S
P
V
D
S
L
S
S
S
S
S
S
Y
D
Dog
Lupus familis
XP_547534
525
56508
V475
P
E
A
E
G
P
A
V
K
R
M
R
L
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S465
E
P
G
E
G
L
S
S
P
A
G
G
S
Y
E
Rat
Rattus norvegicus
O89038
507
54350
S458
E
P
G
E
G
L
S
S
P
A
G
G
S
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
S457
R
S
P
V
D
S
L
S
S
S
S
S
S
Y
D
Chicken
Gallus gallus
Q9W6U8
499
53650
S451
R
S
P
V
D
S
L
S
S
S
S
S
S
Y
D
Frog
Xenopus laevis
Q03413
498
54053
S450
R
S
P
V
D
S
L
S
S
N
A
S
S
F
E
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
G476
V
D
S
I
S
S
N
G
S
S
Y
E
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
A478
Y
E
G
Y
P
Y
R
A
L
M
G
H
N
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
H220
L
G
L
P
G
E
A
H
D
R
R
T
N
E
G
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
N586
N
S
S
N
N
N
S
N
N
G
N
D
N
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
6.6
N.A.
93.3
93.3
N.A.
20
20
20
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
100
100
N.A.
33.3
33.3
26.6
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
16
8
0
31
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
16
31
0
0
0
8
0
0
8
0
8
31
% D
% Glu:
31
16
0
24
0
8
0
0
0
0
0
8
0
8
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
39
0
47
0
0
8
0
8
39
31
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
31
31
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
8
0
0
8
8
8
8
8
8
8
8
0
24
8
0
% N
% Pro:
8
31
31
8
8
8
0
0
31
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
31
0
0
0
0
0
8
0
0
16
8
8
0
0
8
% R
% Ser:
0
39
16
0
8
39
39
62
39
31
24
31
62
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
0
31
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
8
0
0
0
0
8
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _